The University of Melbourne
Browse
1/1
2 files

Altered Outer Retinal Structure, Electrophysiology and Visual Perception in Parkinson’s Disease Study Dataset

Version 2 2023-11-13, 02:33
Version 1 2023-09-14, 11:42
dataset
posted on 2023-11-13, 02:33 authored by Katie Tran, CHRISTINE NGUYENCHRISTINE NGUYEN, BANG BUIBANG BUI, BAO NGUYENBAO NGUYEN, PEI YING LEEPEI YING LEE, DAVID FINKELSTEIN, ALLISON MCKENDRICKALLISON MCKENDRICK

This dataset is from a pilot cross-sectional study where we considered whether clinically implementable measures targeting outer retinal function and structure can differentiate Parkinson's disease (PD) from healthy ageing in a similar manner to previously reported inner retinal outcomes. As a proof of principle, we also considered whether outer retinal biomarkers are sensitive to patients’ standard intraday levodopa (L-DOPA) dosing regimen. Sixteen people with PD and 21 age-matched controls (aged 41-85 years) participated in this study. Centre-surround perceptual contrast suppression, macular visual field sensitivity, colour discrimination, light-adapted electroretinography and optical coherence tomography were tested. Electroretinography and optical coherence tomography were conducted twice during the visit: before and after a midday L-DOPA dose for PD participants, or repeated after approximately two hours for control participants.

Funding

Multimodal retinal imaging provides "insight" into cerebrovascular ageing

Australian Research Council

Find out more...

Melbourne Neuroscience Institute Interdisciplinary Seed Fund

Melbourne Research Fellowship

Melbourne Neuroscience Institute Fellowship

Melbourne School of Health Sciences Seed Funding

John Landman PhD Scholarship

History

Add to Elements

  • No

Usage metrics

    5000 - Medicine_1

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC