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related tumour simulation

dataset
posted on 2021-08-16, 05:53 authored by Sebastian Hollizeck, Stephen WongStephen Wong, BENJAMIN SOLOMONBENJAMIN SOLOMON, Dineika Chandrananda, SARAH-JANE DAWSONSARAH-JANE DAWSON
Simulated dataset of related tumour samples.<br><br>Reads were firsts simulated with ART then aligned with BWA and variants were spiked in with Bamsurgeon.<br><br>Truth variants were split into somatic (simulating a cancer like allele frequency distribution) and germline (actual sample germline variants at a 0.5 allele frequency)<div><br></div><div><br></div>

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