Exon structure of CALCR mRNA and heatmaps

Figure 2: Structure of CALCR gene and known transcripts (panel A). Exon structure and expression profile of transcripts identified in HGG cell lines using nanopore sequencing. WK1 (panel B), JK2 (panel C) and SB2b (panel D) display expressions of transcript 2 as known CT_a Receptor mRNA and as alternatively spliced novel CT_b Receptor mRNA. In addition, WK1 displays two stochastically expressed novel transcripts (panel B). The heatmaps (panel E) represent the transcript per million (TPM) values of each transcript at indicated timepoints (refer to Figure 4). BL = Baseline.