Figure 3a.pzfx

Figure 3: Correlation between SN RNA and either US or MS RNA 3 days post-stimulation with LRAs. (a) Spearman correlation coefficients and 95% confidence intervals are shown for comparisons between SN RNA and US or MS RNA in total and resting CD4+ T cells after adjustment for repeated measures from the same donor using raw and fold change data following stimulation with LRAs. (b) Scatter plots are shown for the fold change from DMSO and the raw values of each parameter quantified in total (closed) and resting (open) CD4+ T cells. The Spearman correlation coefficients (r) and p values after controlling for multiple observations per donor are shown. Each donor is shown as a different symbol and each LRA a different color. Gray = DMSO, blue = vorinostat, purple = romidepsin, green = panobinostat, orange = JQ1, PMA+PHA = red. *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001.