Prism file for Figure 3b.
Figure 3: Correlation between SN RNA and either US or MS RNA 3 days post-stimulation with LRAs. (
a)
Spearman correlation coefficients and 95% confidence intervals are shown for comparisons between SN RNA and US or MS RNA in total and resting CD4+ T cells after adjustment for repeated measures from the same donor using raw and fold change data following stimulation with LRAs. (
b) Scatter plots are shown for the fold change from DMSO and the raw values of each parameter quantified in total (closed) and resting (open) CD4+ T cells. The Spearman correlation coefficients (r) and p values after controlling for multiple observations per donor are shown. Each donor is shown as a different symbol and each LRA a different color. Gray = DMSO, blue = vorinostat, purple = romidepsin, green = panobinostat, orange = JQ1, PMA+PHA = red. *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001.