Figure 4a-d.pzfx

Figure 4: Detection of MS RNA is associated with detection of plasma HIV RNA following administration of the HDACi panobinostat to PLWH on ART. (a) US, MS, and plasma HIV were measured and the percentage of participants positive for each RNA measure are shown for timepoints prior to panobinostat and (b) on panobinostat treatment. (c) The proportion of participants with a positive plasma HIV RNA according to the amount of MS RNA. (d) Amount of MS RNA compared to samples that were positive for plasma HIV RNA at baseline and all time points on panobinostat treatment. For d, data are shown as media +/- IQR. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.