SUPPLEMENTAL MATERIAL - Characterizing the influence of Cardiorespiratory 4 Fitness on Left Atrial size and function in the general population

SUPPLEMENTAL MATERIAL

Supplementary Table 1. Sex-based multiple linear regression of factors associated with VO₂peak

Supplementary Figure 1. Cohort based scatterplot of the relationship between Peak oxygen uptake (L/min) and A) Left Atrial Volume (n=559); B) Left Atrial Reservoir strain (n=512); C) Left Atrial Conduit Strain (n=512) and D) Contractile Strain (n=512)

Supplementary Figure 2.Cohort based scatterplot of the relationship between Peak oxygen uptake (L/min) and A) Left Atrial Volume (n=304); B) Left Atrial Reservoir strain (n=270); C) Left Atrial Conduit Strain (n=270) and D) Contractile Strain (n=270) in Males

Supplementary Figure 3. Cohort based scatterplot of the relationship between Peak oxygen uptake (L/min) and A) Left Atrial Volume (n=255); B) Left Atrial Reservoir strain (n=242); C) Left Atrial Conduit Strain (n=242) and D) Contractile Strain (n=242) in Females

Supplementary Figure 4. Analysis of LAE and LA/LV in non-athletic males (n=161) and non-athletic females (n=193).

Supplementary Figure 5. Scatterplot of the relationship between Peak oxygen uptake (L/min) and A) LV Volume and B) Heart Rate Reserve

Supplementary Figure 6. Sex based scatterplot of the relationship between Peak oxygen uptake (L/min) and A) Left Atrial Volume (n=205); B) Left Atrial Reservoir strain (n=180); C) Left Atrial Conduit Strain (n=180) and D) Contractile Strain (n=180) in athletes

Supplementary Figure 7. Sex based scatterplot of the relationship between Peak oxygen uptake (L/min) and A) Left Atrial Volume (n=354); B) Left Atrial Reservoir strain (n=332); C) Left Atrial Conduit Strain (n=332) and D) Contractile Strain (n=332) in non-athletes