<p>Powerpoint file containing supplemental figure 1a.</p><p><b><br></b></p><p><b>Supplementary Figure 1: </b>Toxicity and proliferation following treatment with LRAs in total and resting CD4+ T cells. (<b>a</b>) Representative flow gating strategy of total CD4+ T cells from one donor at day 3 post-treatment is shown. Cell viability following treatment with each LRA was quantified by flow cytometry using a live/dead stain following treatment with each LRA in total (<b>b</b>) and resting (<b>c</b>) CD4+ T cells at days 1, 3, and 6. Proliferation was measured by expression of Ki-67 following treatment with each LRA in total (<b>d</b>) and resting (<b>e</b>) CD4+ T cells at days 1, 3, and 6. Data are presented as the mean +/- SEM of three donors performed in duplicate.</p>
