Supplemental figure 1b-e

Supplementary Figure 1: Toxicity and proliferation following treatment with LRAs in total and resting CD4+ T cells. (a) Representative flow gating strategy for one donor at day 3 post-treatment is shown. Cell viability following treatment with each LRA was quantified by flow cytometry using a live/dead stain following treatment with each LRA in total (b) and resting (c) CD4+ T cells at days 1, 3, and 6. Proliferation was measured by expression of Ki-67 following treatment with each LRA in total (d) and resting (e) CD4+ T cells at days 1, 3, and 6. Data are presented as the mean +/- SEM of three donors performed in duplicate.