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Vaccine safety in numbers

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posted on 2021-08-26, 06:20 authored by Paola Villanueva

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Title: Vaccine safety in numbers

We know vaccines protect us, but as with any medicine, we want to understand both the benefits and risks. Bacille Calmette-Guérin (BCG) vaccine is given to children to protect against tuberculosis. BCG (re)vaccination is increasingly being considered in adults for the protection against a variety of infections and diseases.

Despite one century since this vaccine was first used, there is a paucity of data on the safety of BCG vaccination and revaccination in adults. Optimal management strategies for common injection site reactions remain uncertain.

This PhD project investigates the safety of revaccination, the predictors for and the management of adverse reactions, through active safety surveillance within an international clinical trial -‘BCG vaccination to reduce the Impact of COVID-19 in healthcare workers’ (BRACE).