Post dural puncture headache (PDPH)
is a common problem and gold-standard treatment, an epidural blood
patch
(EBP), is costly and resource intensive. An RCT in 2018
demonstrated that a new, less invasive treatment is effective in the obstetric
population. However, a critical gap exists in the literature as this treatment
has not been studied in the non-obstetric population. We report the successful
use of neostigmine and atropine to treat post-dural puncture headache in a
non-obstetric patient to contribute to this literature and spur further formal
studies to investigate its efficacy.